ZFP36L1 Polyklonale Antilichaam, PE Vervoeging

TIS11B is a member of the tristetraprolin family. Tristetraprolin (TTP), or TIS11, is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating cys-his motif. TIS11B is an mRNA binding protein and is known to interact with the 3?-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.

Berg36; BRF1; Butyrate response factor 1; C3H1 type-like 1; cMG1; Early response factor Berg36; EGF response factor 1; EGF-response factor 1; ERF 1; ERF-1; ERF1; Protein TIS11B; RNF162B; TIS11B; TISB_HUMAN; ZFP36L1; Zinc finger protein 36; Zinc finger protein 36 C3H type like 1; zinc finger protein C3H type 36 like 1.

677

Nucleus

Rat

101-200/338

ZFP36L1

PE

KLH conjugated synthetic peptide derived from human ZFP36L1/ERF1

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

496,564nm/578nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

677

Human, Mouse, Dog, Cow, Pig, Horse