ZFX Antilichaam

ZFX Antibody: The X-linked zinc finger protein ZFX is a member of the Kruppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny.

7543

P17010

NP_003401

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell

ZFX Antibody is affinity chromatography purified via peptide column.

Cat. No. 1224 - Daudi Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (94%)

ZFX Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ZFX antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

ZFX antibody is human, mouse and rat reactive. Multiple isoforms of ZFX are known to exist. ZFX antibody will detect isoform 1 and 2 of ZFX.

ZFX

Cat. No. 1223 - Caco-2 Cell Lysate

Cat. No. 11-801 - Human Small Intestine Tissue Slide

Zinc finger protein, X-linked

Homo sapiens

Schneider-Gadicke A, Beer-Romero P, Brown LG, et al. Putative transcription activator with alternative isoforms encoded by human ZFX gene. Nature 1989; 342:708-11.

Galan-Caridad JM, Harel S, Arenzana TL, et al. Zfx controls the self-renewal of embryonic and hematopoietic stem cells. Cell 2007; 129:345-57.

Arenzana TL, Smith-Raska MR, and Reizis B. Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes. Blood 2009; 113:5857-67

ZFX Antibody: ZNF926, Zinc finger X-chromosomal protein

ELISA, WB, IHC-P, IF

71061446

Liquid