ZIP5 Antilichaam

ZIP5 Antibody: The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.

283375

Q6ZMH5

NP_001128667

Human, Mouse

Unconjugated

Primary Antibodies

Homeostasis

ZIP5 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1306 - Human Spleen Tissue Lysate

1 mg/mL

ZIP5 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ZIP5 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

SLC39A5

Cat. No. 10-901 - Human Spleen Tissue Slide

Solute carrier family 39 (metal ion transporter), member 5

Homo sapiens

Dufner-Beattie J, Langmade SJ, Wang F, et al. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J. Biol. Chem.2003; 278:50142-50.

Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch.2004; 447:796-800.

Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta.2003; 1611:16-30.

Wang F, Kim BE, Petris MJ, et al. The mammalian Zip5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells. J. Biol. Chem.2004; 279:51433-41.

ZIP5 Antibody: ZIP5, LZT-Hs7, ZIP5, Zinc transporter ZIP5, Solute carrier family 39 member 5, ZIP-5

ELISA, WB, IHC-P, IF

206597541

Liquid