ZIP8 Antilichaam

ZIP8 Antibody: The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA) . ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.

64116

Q9C0K1

NP_071437

Human

Unconjugated

Primary Antibodies

Immunology

ZIP8 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1306 - Human Spleen Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Mouse: (89%), Rat: (89%)

ZIP8 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ZIP8 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

ZIP8 antibody is predicted to not cross-react with other ZIP family members.

Slc39a8

Cat. No. 10-901 - Human Spleen Tissue Slide

Solute carrier family 39 (zinc transporter), member 8

Homo sapiens

Dufner-Beattie J, Langmade SJ, Wang F, et al. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J. Biol. Chem.2003; 278:50142-50.

Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch.2004; 447:796-800.

Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta.2003; 1611:16-30.

Dalton TP, He L, Wang B, et al. Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis. Proc. Natl. Acad. Sci. USA2005; 102:3401-6.

ZIP8 Antibody: ZIP8, PP3105, BIGM103, LZT-Hs6, ZIP8, Zinc transporter ZIP8, BCG-induced integral membrane protein in monocyte clone 103 protein

ELISA, WB, IHC-P, IF

205830403

Liquid