ZIPK-antilichaam

ZIPK Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues.

1613

O43293

BAA81746

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Apoptosis, Autophagy, Cancer

ZIPK Antibody is affinity chromatography purified via peptide column.

Cat. No. 1201 - HeLa Cell Lysate

1 mg/ml

ZIPK Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ZIPK antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

DAPK3

Cat. No. 1205 - Jurkat Cell Lysate

Cat. No. 1306 - Human Spleen Tissue Lysate

Cat. No. 1208 - THP-1 Cell Lysate

Cat. No. 17-005 - Jurkat Cell Slide

Death-associated protein kinase 3

Homo sapiens

Kawai T, Matsumoto M, Takeda K, Sanjo H, Akira S. ZIP kinase, a novel serine/threonine kinase which mediates apoptosis. Mol Cell Biol 1998;18:1642-51 (RD1299)

ZIPK Antibody: ZIP, ZIPK, Death-associated protein kinase 3, DAP-like kinase, DAP kinase 3

ELISA, WB, ICC, IF

5162884

Liquid