ZM-447439
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ZM-447439 is a selective ATP-competitive inhibitor of Aurora kinase B1 (IC50 = 50 nM, Aur A IC50 = 1 µM, Aur C IC50 = 250 nM at physiological ATP concentrations2, Ref.1 lists Aur A IC50 = 110nM and Aur B IC50 = 113nM) . It did not significantly inhibit a panel of 14 other kinases including mitotic kinases CDK1 and PLK1. It prevents chromosome alignment, spindle checkpoint function and cytokinesis.1,2
Unconjugated
White solid
RT
Beschrijving
ZM-447439 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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