ZNF384 Antilichaam - C-terminal regio : HRP (ARP39804_P050-HRP)

Zinc finger protein 384

NP, CIZ, NMP4, CAGH1, ERDA2, TNRC1, CAGH1A

171017

Q8TF68-3

NP_001035009

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.

SOX2; UBC; OPTN; tat; HOXC9; CEBPE; TAF15; ZYX; PCBP1; VIM

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

ZNF384 is strongly supported by BioGPS gene expression data to be expressed in PANC1

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Wet Ice

461

ZNF384

ZNF384

Rabbit

Zinc finger protein 384

NM_001039920

QQPPPHFQSPGAAPQGGGGGDSNPNPPPQCSFDLTPYKTAEHHKDICLTV