ZNF446 Antilichaam - C-terminal regio : HRP (ARP39319 T100-HRP)

Zinc finger protein 446

ZSCAN30, ZSCAN52, ZKSCAN20

55663

Q9NWS9

NP_060378

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF446

ZNF446 contains a KRAB and three C (2) H (2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE and AP-1, suggesting that the ZNF446 protein may act as a transcriptional repressor in mitogen-activated protein kinase (MAPK) signaling pathway to mediate cellular functions.

NOTCH2NL; KRTAP10-3; ZSCAN22; ZNF396; KRT40; ZNF496; PGBD1; LZTS2; ZNF397; ZSCAN16; ZKSCAN7; ZNF446; ZSCAN32; ZNF232; ZSCAN9; ZNF165; ZSCAN21; ZNF24; TRIM27; PIN1; DGCR6; ACTN2; FHL5; DGCR6L; SUFU; ZNF263

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 75%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

49kDa

Liu, F., et al., (2005) Biochem. Biophys. Res. Commun. 333 (1), 5-13

Wet Ice

450

ZNF446

ZNF446

Rabbit

Zinc finger protein 446

NM_017908

SYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRK