ZNF521 (NM 015461) Humaan Recombinant Proteïne

Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes.[UniProtKB/Swiss-Prot Function]

Purified recombinant protein of Human zinc finger protein 521 (ZNF521), Lys1077-Glu1150, with N-terminal His-ABP tag, expressed in E. coli, 50ug

EHZF; Evi3

25925

Q96K83

NM_015461

18q11.2

E. coli

N-His-ABP

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.

22.6 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

ZNF521

Human

NP_056276

https://www.ncbi.nlm.nih.gov/gene/25925

https://www.uniprot.org/uniprot/Q96K83

https://www.ncbi.nlm.nih.gov/nuccore/NM_015461

https://www.ncbi.nlm.nih.gov/nuccore/NP_056276