ZNRF2 Polyklonale Antilichaam
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s) . ZNRF2 (zinc and ring finger 2), also known as RNF202, is a 242 amino acid peripheral membrane protein that contains one RING-type zinc finger and localizes to the lysosome, as well as the endosome and the cell junction. Expressed at high levels in brain tissue, ZNRF2 is thought to function as an E3 ubiquitin-protein ligase that may be involved in the establishment and maintenance of neuronal transmission and plasticity. Upon DNA damage, ZNRF2 is subject to phosphorylation, probably by ATR or ATM.
E3 ubiquitin-protein ligase ZNRF2; Protein Ells2; RING finger protein 202; Zinc/RING finger protein 2; Znrf2; ZNRF2_HUMAN.
223082
• Rabbit
Human, Mouse, Rat
151-242/242
ZNRF2
• Polyclonal
• IgG
Unconjugated
KLH conjugated synthetic peptide derived from human ZNRF2
WB, ELISA, IHC-P, IHC-F, IF
Purified by Protein A.
1µg/µl
WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:50-200)
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
223082
Beschrijving
ZNRF2 Polyklonale Antilichaam Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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