
Zoledroninezuur
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Potent inhibitor of bone resorption (IC50 = 2 nM in mouse calvarial cultures) .1 The mechanism of its action is thought to be via inhibition of osteoclastic activity, induction of osteoclast apoptosis and blockage of osteoclastic resorption of mineralized bone and cartilage through its binding to bone. Clinically useful drug for treatment of osteoporosis2, hypercalcemia of malignancy (HCM), multiple myeloma and bone metastases from solid tumors3. It has also been investigated as an antitumor agent and showing efficacy as an adjuvant therapy in several cancers.4,5
Unconjugated
White or off-white solid
-20°C
Beschrijving
Zoledroninezuur Beschikbaar in 25 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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