ZRANB1 Antilichaam

ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.

54764

Q9UGI0

Q9UGI0

Human, Mouse

This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-692 amino acids from the C-terminal region of human ZRANB1.

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Bovine

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

81 kDa

Rabbit Ig

ZRANB1

Ubiquitin thioesterase ZRANB1

Homo sapiens

Tran, H., et al. Genes Dev. 22 (4) :528-542 (2008)

Evans, P.C., et al. Biochem. J. 357 (PT 3), 617-623 (2001)

Ubiquitin thioesterase ZRANB1, TRAF-binding domain-containing protein, hTrabid, Zinc finger Ran-binding domain-containing protein 1, ZRANB1, TRABID

WB, IHC-P

212276487

Liquid