17-Trifluormethylfenyl-13,14-dihydrotrinor prostaglandine F1α

17-Trifluoromethylphenyl-13,14-dihydro trinor prostaglandin F1α (Compound 8) is a saturated prostaglandin analogue. 17-Trifluoromethylphenyl-13,14-dihydro trinor prostaglandin F1α has good affinity and receptor selectivity for human prostaglandin F receptor (hFP receptor) witn an EC50 of 85 nM[1].

1027401-98-4

17-TFM-PGF1α

12352005

H225-H319-H336

Prostaglandin Receptor

GPCR/G Protein

Others

FC(F)(F)C1=CC=CC(CC[C@H](O)CC[C@@H]2[C@H]([C@H](C[C@H]2O)O)CCCCCCC(O)=O)=C1

C24H35F3O5

460.53

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

[1]deLong MA, et al. Synthesis and in vitro evaluation of human FP-receptor selective prostaglandin analogues. Bioorg Med Chem Lett. 2000 Jul 17;10 (14) :1519-22.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-23190/

Reference compound1

No Development Reported