ACSL3 Antilichaam - N-terminalgebied: HRP (ARP46453 P050-HRP)

Acyl-CoA synthetase long-chain family member 3

ACS3, FACL3, LACS3, LACS 3, PRO2194

2181

O95573

NP_004448

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human ACSL3

ACSL3 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.

UBC; SUMO2; STAU1; HIPK4; PPP6R1; PPP6R2; MAPK4; YES1; vpu; LYN; MTHFD1; ACSL4; APP; UBD; SIRT7; NDRG1; TMEM173; SPG20

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

There is BioGPS gene expression data showing that ACSL3 is expressed in HEK293T

0.5 mg/ml

Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

80kDa

Yao, H. (2008) J. Biol. Chem. 283 (2), 849-854

Wet Ice

720

ACSL3

ACSL3

Rabbit

Long-chain-fatty-acid--CoA ligase 3

NM_004457

LDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKI