ADAM17 Antilichaam - C-terminalgebied: HRP (ARP61304 P050-HRP)

CSVP, TACE, NISBD, ADAM18, CD156B, NISBD1

6868

P78536

NP_003174

Human

The immunogen is a synthetic peptide directed towards the C-terminal region of Human ADAM17

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.

UBC; EED; PXN; TNFRSF1B; TNFRSF1A; PDIA3; FBXO6; SH3D19; TGFA; MAD2L2; PTPN3; TNFSF11; FHL2; MAD2L1; DLG1; ERBB4; TNF; NOTCH1; TIMP3; MAPK1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

90kDa

Wet Ice

824

ADAM17

ADAM17

Rabbit

DGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC