ADAR Antibody - N-terminal regio : HRP (ARP36715 P050-HRP)

Adenosine deaminase, RNA-specific

DSH, AGS6, G1P1, IFI4, P136, ADAR1, DRADA, DSRAD, IFI-4, K88DSRBP

103

P55265

NP_001102

Human

The immunogen is a synthetic peptide directed towards the N terminal region of human ADAR

ADAR is responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UBC; SUMO2; SUMO3; STAU1; STAU2; SUMO1; RPA3; RPA2; RPA1; ERG; SUZ12; EED; EZH2; BMI1; RNF2; rev; FBXO6; TARDBP; UBE2I; HDAC9; XPO1; WHSC1; TGM2; SNRPN; SNRPB; UPF1; DHX9; DDX17; HNRNPM; CAND1; CUL3; HNRNPA1; ELAVL1; HDAC5; tat; ADAR; HDLBP

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

136kDa

Zhang, F., (2008) J. Dermatol. Sci. 50 (2), 109-114

Wet Ice

1226

ADAR

ADAR

Rabbit

Double-stranded RNA-specific adenosine deaminase

NM_001111

GEGKATTAHDLSGKLGTPKKEINRVLYSLAKKGKLQKEAGTPPLWKIAVS