ADCY4 Antilichaam

This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP) . Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.

196883

Q8NFM4

Q8NFM4

Human

This ADCY4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-441 amino acids from the Central region of human ADCY4.

Unconjugated

Primary Antibodies

Cancer, Obesity, Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

120 kDa

Rabbit Ig

ADCY4

Adenylate cyclase type 4

Homo sapiens

Rhim, J.H., et al. Aging Cell 5 (6) :451-461 (2006)

Jiang, G., et al. Am. J. Physiol. Endocrinol. Metab. 284 (4), E671-E678 (2003)

Sunahara, R.K., et al. Mol. Interv. 2 (3) :168-184 (2002)

Ludwig, M.G., et al. J. Recept. Signal Transduct. Res. 22 (1-4), 79-110 (2002)

Adenylate cyclase type 4, ATP pyrophosphate-lyase 4, Adenylate cyclase type IV, Adenylyl cyclase 4, ADCY4

WB, Flow

25008336

Liquid