AHCY Antibody - N-terminal regio : HRP (ARP51768 P050-HRP)

Adenosylhomocysteinase

SAHH, adoHcyase

191

P23526

NP_000678

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human AHCY

S-adenosylhomocysteine hydrolase catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy) . Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family.S-adenosylhomocysteine hydrolase catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy) . Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

ANKRD40; C1orf50; APPBP2; HUWE1; UBC; FUS; AHCY; SUMO2; SUMO3; SUMO1; NEDD8; ASB16; MSN; MC1R; HK1; HEXA; HDGF; FH; EEF1A2; DHX15; CAPZB; ATIC; ACAT2; H2AFV; NSFL1C; OGFOD1; PAPSS1; UBA3; TBCE; PYGL; HECW2; FBXO6; YWHAQ; gag-pol; PXN; DAB2; ATF2; TRAF3IP1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 86%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

48kDa

Li, Q.S., (2008) Biochemistry 47 (17), 4983-4991

Wet Ice

432

AHCY

AHCY

Rabbit

Adenosylhomocysteinase

NM_000687

SDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIA