AMOT Antibody - N-terminal regio : HRP (ARP34661_P050-HRP)

Angiomotin

KIAA1071

154796

Q4VCS5

NP_573572

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human AMOT

AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

AMOT; C1orf216; WDYHV1; MED4; SNAPC5; PPP2R4; LURAP1; UNC119; LMO4; PIN1; MAGEA4; KRT31; KRT15; FUS; SEPT1; CEP76; HAUS2; LATS2; CEP250; CDKN1A; ACTB; ACTA1; YAP1; SART3; AURKB; MAPK3; BAG3; WWOX; ITCH; LATS1; YWHAG; UBC; PARK2; AMOTL1; SPICE1; MPP7; CNTR

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

AMOT is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

72kDa

Holmgren, L., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (24), 9208-9213

Wet Ice

675

AMOT

AMOT

Rabbit

Angiomotin

NM_133265

TANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNE