Anti-bijlagein-4/ANXA4 Antibody Picoband® fluoro550 Vervoeging

ANXA4 (Annexin A4), also known as ANX4, is a protein that in humans is encoded by the ANXA4 gene. It belongs to the annexin family of calcium-dependent phospholipid binding proteins. By PCR analysis of somatic cell hybrids and in situ hybridization with a cDNA probe, the human ANXA4 gene is mapped to chromosome 2p13. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. And ANXA4 is almost exclusively expressed in epithelial cells.

Annexin A4;35-beta calcimedin; Annexin IV; Annexin-4; Carbohydrate-binding protein p33/p41; Chromobindin-4; Endonexin I; Lipocortin IV; P32.5; PP4-X; Placental anticoagulant protein II; PAP-II; Protein II; ANXA4; ANX4

ANXA4

307

P09525

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human Annexin-4/ANXA4 recombinant protein (Position: M1-D319) .

Expressed at high levels in lung, placenta and thymus and at lower levels in ovary, intestine and brain.

Flow Cytometry

Calcium Binding Proteins, Calcium Signaling, Cardiovascular, Cell Adhesion, Cytoskeleton/ECM, Signal Transduction, Signaling Pathway

Immunogen affinity purified.

Liquid

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. .

1. Barrow, L. L., Simin, K., Jones, J. M., Lee, D. C., Meisler, M. H. Conserved linkage of early growth response 4, annexin 4, and transforming growth factor alpha on mouse chromosome 6. Genomics 19: 388-390, 1994. 2. Fukuoka, S.-I., Kern, H., Kazuki-Sugino, R., Ikeda, Y. Cloning and characterization of ZAP36, an annexin-like, zymogen granule membrane associated protein, in exocrine pancreas. Biochim. Biophys. Acta 1575: 148-152, 2002. 3. Tait, J. F., Smith, C., Frankenberry, D. A., Miao, C. H., Adler, D. A., Disteche, C. M. Chromosomal mapping of the human annexin IV (ANX4) gene. Genomics 12: 313-318, 1992.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

35883 MW

6

Annexin A4

Nucleus.

Annexin A4

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.