Anti-CD8b, Mouse(H35-17.2)

This rat monoclonal antibody reacts with the mouse CD8 beta molecule. The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

9007-83-4

CD8b antigen; CD8 antigen beta polypeptide 1 (p37) ; CD8 beta; CD8B1; Leu2; Ly3; LYT3; P37; T lymphocyte surface glycoprotein beta chain; T-cell surface glycoprotein CD8 beta chain

41116161

Primary and secondary antibodies for multiple methodology immunostaining detection application

Cd8b1 (Mouse)

12526

3331

P10300

P10300

CD8b

Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c

CD8b,

H35-17.2

Primary

Animal

Animal

Flow, surface (published) |Functional studies (published)

MPBMC's or Thymus.

2 years

0.2 mg/mL

PBS, 0.05% BSA, 0.05% azide

37 kDa

Note: References for this clone sold by other suppliers may be listed for expected applications. Infection Immunity (1994) 62(5): 1820-1829. (functional studies) Meth Mol Biol vol 1559. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6786-5_2 (Flow, surface)

RT (ND)

Stable at room temperature or 37°C (98°F) for 7 days.

Guaranteed for at least 24 months from date of receipt when stored as recommended

https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf

IgG2b, kappa

Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

Purified, with BSA