Anti-Connexin 40/GJA5 Antibody Picoband® fluoro550 Vervoeging

Connexin proteins oligomerize to form intercellular channels, called gap junctions, through which ions and small molecules move between adjacent cells. Connexin 40 (Gap junction alpha-5 protein) is a protein that in humans is encoded by the GJA5 gene.This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.

Gap junction alpha-5 protein; Connexin-40; Cx40; GJA5

GJA5

2702

P36382

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 40/GJA5, identical to the related mouse and rat sequences.

Flow Cytometry

Cardiovascular, Cell Adhesion, Cytoskeleton/ECM, Signal Transduction, Vasculature

Immunogen affinity purified.

Liquid

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

1. Entrez Gene: GJA5 gap junction protein, alpha 5, 40kDa

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

40380 MW

No cross reactivity with other proteins.

6

Gap junction alpha-5 protein

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Belongs to the connexin family. Beta-type (group I) subfamily.

Gap junction alpha-5 protein

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.