Anti-Ep-CAM / CD326 (Extracellulair Domain) (Epithelial Marker) Monoklonale Antilichaam (Kloon: EGP40/826) -CF488

Recognizes a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM) . Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been sμggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.

Adenocarcinoma-associated Antigen; Cell Surface Glycoprotein Trop-1; EGP2; EGP314; EGP40; Epithelial Cell Adhesion Molecule; Epithelial Glycoprotein 314; ESA; KSA; TACD1; TROP1; Tumor-associated Calcium Signal Transducer 1 (TACSTD1)

TACSTD1

4072

P16422

Human

A synthetic peptide (around aa 20-60) from the N-terminus of human TACSTD1 protein

EGP40/826

FACS, IF

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous.

Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood) ; Immunofluorescence (1:50-1:100)

Mouse IgG1, kappa

CF488