Anti-fibroblast groeifactor 22 FGF22 Antibody Picoband® fluoro594 Vervoeging

FGF22, Fibroblast growth factor 22, is a protein which in humans is encoded by the FGF22 gene. The FGF22 sequence in a genomic clone is assigned to 19p13.3. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. In situ hybridization demonstrated expression in the inner root sheath of the hair follicle. FGF22 is involved in hair development.

Fibroblast growth factor 22; FGF-22; FGF22; UNQ2500/PRO5800

FGF22

27006

Q9HCT0

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence in the middle region of human FGF22, different from the related mouse and rat sequences by one amino acid.

Flow Cytometry

Growth Factors/Hormones, Signal Transduction

Immunogen affinity purified.

Liquid

Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro) . May be involved in hair development. .

1. Nakatake, Y., Hoshikawa, M., Asaki, T., Kassai, Y., Itoh, N.Identification of a novel fibroblast growth factor, FGF-22, preferentially expressed in the inner root sheath of the hair follicle.Biochim. Biophys. Acta 1517: 460-463, 2001. 2. Terauchi, A., Johnson-Venkatesh, E. M., Toth, A. B., Javed, D., Sutton, M. A., Umemori, H.Distinct FGFs promote differentiation of excitatory and inhibitory synapses.Nature 465: 783-787, 2010. 3. Umemori, H., Linhoff, M. W., Ornitz, D. M., Sanes, J. R. FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain.Cell 118: 257-270, 2004.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

19663 MW

No cross reactivity with other proteins.

6

Fibroblast growth factor 22

Secreted .

Belongs to the heparin-binding growth factors family.

Fibroblast growth factor 22 (FGF-22)

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.