Anti-METTL11A/NTMT1 Antibody Picoband® fluoro488 Vervoeging

The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1; MIM 179710) . METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200) .

Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3

NTMT1

28989

Q9BV86

Human

No cross-reactivity with other proteins

E.coli-derived human METTL11A/NTMT1 recombinant protein (Position: K21-R223) .

Ubiquitous. Highly expressed in brain. .

Flow Cytometry

Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Tumor Biomarkers

Immunogen affinity purified.

Liquid

Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.

1. Gross, M. B. Personal Communication. Baltimore, Md. 7/17/2014. 2. Schaner Tooley, C. E., Petkowski, J. J., Muratore-Schroeder, T. L., Balsbaugh, J. L., Shabanowitz, J., Sabat, M., Minor, W., Hunt, D. F., Macara, I. G. NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein. Nature 466: 1125-1128, 2010.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

41409 MW

6

Protein NDRG3

Membrane ; Single-pass type I membrane protein .

Protein NDRG3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.