Anti-Neurotensine Receptor 1/NTSR1 Antibody Picoband® 31.0550 Vervoeging

Neurotensin receptor type 1 is a protein that in humans is encoded by the NTSR1 gene. Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.

Thioredoxin, mitochondrial; MTRX; Mt-Trx; Thioredoxin-2; TXN2; TRX2

NTSR1

4923

P30989

Human

No cross-reactivity with other proteins.

E.coli-derived human Neurotensin Receptor 1/NTSR1 recombinant protein (Position: A15-D400) .

Widely expressed in adult (at protein level) and fetal tissues.

Flow Cytometry

Hematopoietic Progenitors, Immunology, Innate Immunity, Stem Cells, Surface Molecules

Immunogen affinity purified.

Liquid

Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.

1. Huang, W., Masureel, M., Qu, Q., Janetzko, J., Inoue, A., Kato, H. E., Robertson, M. J., Nguyen, K. C., Glenn, J. S., Skiniotis, G., Kobilka, B. K. Structure of the neurotensin receptor 1 in complex with beta-arrestin 1. Nature 579: 303-308, 2020. 2. Kato, H. E., Zhang, Y., Hu, H., Suomivuori, C.-M., Kadji, F. M. N., Aoki, J., Krishna Kumar, K., Fonseca, R., Hilger, D., Huang, W., Latorraca, N. R., Inoue, A., Dror, R. O., Kobilka, B. K., Skiniotis, G. Conformational transitions of a neurotensin receptor 1-G (i1) complex. Nature 572: 80-85, 2019. 3. Laurent, P., Clerc, P., Mattei, M.-G., Forgez, P., Dumont, X., Ferrara, P., Caput, D., Rostene, W. Chromosomal localization of mouse and human neurotensin receptor genes. Mammalian Genome 5: 303-306, 1994.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Thioredoxin 2

Mitochondrion.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.