Anti-NLRP7 Antibody Picoband®

NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

Boster Bio Anti-NLRP7 Antibody Picoband® catalog # A07838-1. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Protein SOX-15; Protein SOX-12; Protein SOX-20; SOX15; SOX12; SOX20; SOX26; SOX27

NLRP7

199713

Q8WX94

Human

No cross-reactivity with other proteins.

E.coli-derived human NLRP7 recombinant protein (Position: M1-L169) .

Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

ELISA, Flow Cytometry, IHC, WB

Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Binds to the 5'-AACAAT-3' sequence.

1. Agarwal, P., Bagga, R., Jain, V., Kalra, J., Gopalan, S. Familial recurrent molar pregnancy: a case report. Acta Obstet. Gynecol. Scand. 83: 213-214, 2004. 2. Aghajanova, L., Mahadevan, S., Altmae, S., Stravreus-Evers, A., Regan, L., Sebire, N., Dixon, P., Fisher, R. A., Van den Veyver, I. B. No evidence for mutations in NLRP7, NLRP2 or KHDC3L in women with unexplained recurrent pregnancy loss or infertility. Hum. Reprod. 30: 232-238, 2015. 3. Andreasen, L., Bolund, L., Niemann, I., Hansen, E. S., Sunde, L. Mosaic moles and non-familial biparental moles are not caused by mutation in NLRP7, NLRP2 or C6orf221. Molec. Hum. Reprod. 18: 593-598, 2012.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A07838-1

49229 MW

112 kDa

6

SRY-box 15

Nucleus.

Chromaffin granule amine transporter

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.