Anti-pan cytokeratine-antilichaam (monoclonaal, PCK-26)
Gecertificeerd

Anti-pan cytokeratine-antilichaam (monoclonaal, PCK-26)

Catalog #: MA1082
Maat: 100 µg/Vial

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
Login voor prijs
BTW niet inbegrepen
Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin (mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues.

Description

Boster Bio Anti-Pan cytokeratin Antibody (Monoclonal, PCK-26) catalog # MA1082. Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse.

Synonyms

Keratin, type II cytoskeletal 8; Cytokeratin endo A; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8; Krt8; Krt2-8

Gene Name

Krt8

Gene ID

25626

UniProt

Q10758

Host

• Mouse

Reactivity

Human, Mouse

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

Cytokeratin from human epidermis.

Clonality

• Monoclonal

Clone

Clone: PCK-26

Tissue Specificity

Expressed in cardiac and striated muscle. Expressed at Z-lines within the muscle fibers and at Z-line and M- line domains at costameres at the sarcolemmal membrane (at protein level) . Observed in coagulating gland, bladder, salivary gland, kidney, spleen, thymus, lung and heart. Also observed in ventral prostate, seminal vesicle and liver where expression increases following castration. .

Applications

IF, IHC, WB

Field of Research

Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Keratin, Signal Transduction

Purification

Ascites

Concentration

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Form

Lyophilized

Reconstitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Function

Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. .

References & Citations

1. Rastaldi MP et al. Glomerular podocytes contain neuron-like functional synaptic vesicles. FASEB J 20:976-8 (2006) . 2. Wen J et al. Use of superparamagnetic microbeads in tracking subretinal injections. Mol Vis 11:256-62 (2005) .

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product MSDS

https://www.bosterbio.com/msds?sku=MA1082

Calculated Molecular Weight

54019 MW

Observed Molecular Weight

54 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Keratin, type II cytoskeletal 8

Subcellular Location

Cytoplasm . Nucleus, nucleoplasm . Nucleus matrix .

Sequence Similarities

Belongs to the intermediate filament family.

Protein Name

Keratin, type II cytoskeletal 5

Isotype

Mouse IgG1

Contents

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Beschrijving

Boster Bio Anti-Pan cytokeratin Antibody (Monoclonal, PCK-26) catalog # MA1082. Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse.

Specificaties

ProductnaamAnti-pan cytokeratine-antilichaam (monoclonaal, PCK-26)
Categorie
Beschikbare grootte100 µg/Vial
CatalogusnummerMA1082