Anti-PI 3 Kinase klasse 3 PIK3C3 Konijn Monoklonale Antilichaam

Boster Bio Anti-PI 3 Kinase Class 3 PIK3C3 Rabbit Monoclonal Antibody catalog # M02356. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Phosphatidylinositol 3-kinase catalytic subunit type 3; PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3;2.7.1.137; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34; PIK3C3; VPS34

PIK3C3

5289

Q8NEB9

Human, Mouse, Rat

A synthesized peptide derived from human PI 3 Kinase Class 3

Clone: CDO-16

Ubiquitously expressed, with a highest expression in skeletal muscle. .

WB, IHC

Immunology, Innate Immunity, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipid Signaling, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Signaling Pathway, TLR Signaling

Affinity-chromatography

0.5mg/ml

Liquid

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530) . Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02356

101549 MW

100 kDa

Phosphatidylinositol 3-kinase catalytic subunit type 3

Midbody . Late endosome . Cytoplasmic vesicle, autophagosome . As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes (Probable) . Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity) . .

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.