Anti-Selenocysteïne lyase SCLY Antibody Picoband® fluoro550 Vervoeging

SCLY (Selenocysteine Lyase), is an enzyme that catalyzes the chemical reaction. This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The International Radiation Hybrid Mapping Consortium mapped the human SCLY gene to chromosome 2. Mihara et al. (2000) showed that mouse Scly catalyzed the conversion of L-selenocysteine to L-alanine. Scly activity required pyridoxal 5-prime phosphate, was specific to L-selenocysteine, and showed maximum reactivity at pH 9.0.

Selenocysteine lyase; hSCL;4.4.1.16; SCLY; SCL

SCLY

51540

Q96I15

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human SCLY.

Expressed in many tissues, with the highest level in heart and skeletal muscle, intermediate levels in brain, kidney, pancreas and liver, and low levels in placenta and lung. .

Flow Cytometry

Amino Acid Metabolism, Amino Acids, Cofactors, Vitamins/Minerals, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Vitamins/Minerals

Immunogen affinity purified.

Liquid

Catalyzes the decomposition of L-selenocysteine to L- alanine and elemental selenium. .

1. Mihara, H., Kurihara, T., Watanabe, T., Yoshimura, T., Esaki, N. cDNA cloning, purification, and characterization of mouse liver selenocysteine lyase: candidate for selenium delivery protein in selenoprotein synthesis. J. Biol. Chem. 275: 6195-6200, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

48149 MW

No cross reactivity with other proteins.

6

Selenocysteine lyase

Cytoplasm, cytosol .

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

Selenocysteine lyase

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.