Anti-Somatostatine Receptor 1/SSTR1 Antibody Picoband® 0,00647 Vervoeging

SSTR1 (Somatostatin receptor type 1) is a protein that in humans is encoded by the SSTR1 gene. The SSTR1 gene is mapped to chromosome 14. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach.

Somatostatin receptor type 1; SS-1-R; SS1-R; SS1R; SRIF-2; SSTR1

SSTR1

6751

P30872

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human Somatostatin Receptor 1, identical to the related rat and mouse sequences.

Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.

Flow Cytometry

More Gpcr, Neurology Process, Neuropeptides, Neuroscience, Neurotransmission, Neurotransmitter, Receptors / Channels

Immunogen affinity purified.

Liquid

Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na (+) /H (+) exchanger via pertussis toxin insensitive G proteins.

1. Kubota, A., Yamada, Y., Kagimoto, S., Shimatsu, A., Imamura, M., Tsuda, K., Imura, H., Seino, S., Seino, Y.Identification of somatostatin receptor subtypes and an implication for the efficacy of somatostatin analogue SMS 201-995 in treatment of human endocrine tumors.J. Clin. Invest. 93: 1321-1325, 1994. 2. Yamada, Y., Post, S. R., Wang, K., Tager, H. S., Bell, G. I., Seino, S.Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.Proc. Nat. Acad. Sci. 89: 251-255, 1992.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

42686 MW

No cross reactivity with other proteins.

6

Somatostatin receptor type 1

Cell membrane; Multi-pass membrane protein.

Belongs to the transcription factor STAT family.

Somatostatin receptor type 1 (SS-1-R/SS1-R/SS1R)

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.