Anti-Tenascine TNN Antilichaam (monoclonaal, BC-24)

The tenascins are a family of extracellular matrix proteins (ECMs) . Tenascin is an extracellular matrix protein. It expressed in an unusually restricted pattern during embryogenesis and has been implicated in a variety of morphogenetic phenomena. Human hexabrachion gene (tenascin) is mapped to chromosome 9, bands q32-q34. The coding region of the hexabrachion gene spans approximately 80 kilobases of DNA and consists of 27 exons separated by 26 introns.

Boster Bio Anti-Tenascin TNN Antibody (Monoclonal, BC-24) catalog # MA1094. Tested in IHC, ICC, WB applications. This antibody reacts with Human.

Protein Tnn ; Tnn

TNN

Human (63923), Mouse (329278), Rat (304913)

Q9UQP3

Human

No cross-reactivity with other proteins

Human tenascin.

Clone: BC-24

Expressed in neurons. The larger forms (isoform tau-A and isoform tau-B) are preferentially expressed in the peripheral nervous system while the other are expressed in the central nervous system. Low amounts of the larger forms are also found in limited areas of the CNS.

IHC, ICC, WB

Actin, etc., Cardiovascular, Contractility, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Ascites

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Lyophilized

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

TNN: Involved in neurite outgrowth and cell migration inhippocampal explants.

1. Saga, Y.; Yagi, T.; Ikawa, Y.; Sakakura, T.; Aizawa, S. : Mice develop normally without tenascin. Genes Dev. 6: 1821-1831, 1992. 2. Gulcher, J. R.; Alexakos, M. J.; Le Beau, M. M.; Lemons, R. S.; Stefansson, K. :Chromosomal localization of the human hexabrachion (tenascin) gene and evidence for recent reduplication within the gene. Genomics 6: 616-622, 1990. 3. Gulcher, J. R.; Nies, D. E.; Alexakos, M. J.; Ravikant, N. A.; Sturgill, M. E.; Marton, L. S.; Stefansson, K. : Structure of the human hexabrachion (tenascin) gene. Proc. Nat. Acad. Sci. 88: 9438-9442, 1991.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=MA1094

173250 MW

272 kDa

No cross reactivity with other proteins.

Tenascin N

TNN: Secreted, extracellular space, extracellularmatrix.|Tnn: Secreted, extracellular space, extracellularmatrix.

Belongs to the tenascin family.

Tenascin-N

Mouse IgG1

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.