Anti-vetzuurbindingseiwit 5/FAKP5 Antilichaampicoband® fluoro550 Vervoeging

FABP5, Fatty acid-binding protein, epidermal, is a protein that in humans is encoded by the FABP5 gene. This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. It is mapped to 8q21.13. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is though that FABPs roles include fatty acid uptake, transport, and metabolism.

Fatty acid-binding protein, epidermal; Epidermal-type fatty acid-binding protein; E-FABP; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; PA-FABP; FABP5

FABP5

2171

Q01469

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the N-terminus of human Fatty Acid Binding Protein 5.

Keratinocytes; highly expressed in psoriatic skin.

Flow Cytometry

Cancer, Cardiovascular, Fatty Acid Oxidation, Fatty Acids, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Redox Metabolism, Signal Transduction

Immunogen affinity purified.

Liquid

High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.

1. Hertzel, A. V., Bernlohr, D. A.Cloning and chromosomal location of the murine keratinocyte lipid-binding protein gene.Gene 221: 235-243, 1998. 2. Siegenthaler, G., Hotz, R., Chatellard-Gruaz, D., Didierjean, L., Hellman, U., Saurat, J. H.Purification and characterization of the human epidermal fatty acid-binding protein: localization during epidermal cell differentiation in vivo and in vitro.Biochem J. 302: 363-371, 1994.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

15164 MW

No cross reactivity with other proteins.

6

Fatty acid-binding protein, epidermal

Cytoplasm.

Belongs to the IAP family.

Fatty acid-binding protein, epidermal

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.