Antisemaforine 3B/SEMA3B Antibody Picoband® (monoclonaal, 9C4F7)

Semaphorin-3Bis aproteinthat in humans is encoded by theSEMA3Bgene. It is mapped to 3p21.31. The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis.

T-complex protein 1 subunit gamma; TCP-1-gamma; CCT-gamma; hTRiC5; CCT3; CCTG; TRIC5

SEMA3B

7869

Q13214

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human Semaphorin 3B/SEMA3B recombinant protein (Position: Y55-R624) .

Clone: 9C4F7

Ubiquitously expressed with highest levels in spleen, thymus and immature brain.

Flow Cytometry

Chaperones, Protein Trafficking, Signal Transduction

Immunogen affinity purified.

Liquid

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

1. Ochi K, Mori T, Toyama Y, Nakamura Y, Arakawa H (2002) . Identification of semaphorin3B as a target of p53. Neoplasia. 4 (1) : 82–7. 2. Tse C, Xiang RH, Bracht T, Naylor SL (January 2002) . Human Semaphorin 3B (SEMA3B) located at chromosome 3p21.3 suppresses tumor formation in an adenocarcinoma cell line. Cancer Research. 62 (2) : 542–6.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Chaperonin containing TCP1 subunit 3

Cytoplasm.

Mouse IgG2b

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.