ARFRP1 Polyklonale Antilichaam, RBITC Vervoeging

The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins. ARFs influence vesicle trafficking and signal transduction in eukaryotic cells and they play a central role in the maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D (PC-PLD) . ARFRP1 (ADP-ribosylation factor related protein 1), also known as ARP or ARL18, is a 201 amino acid membrane-associated GTPase that localizes to the plasma membrane and the Golgi apparatus and is related to the ARF family of regulatory proteins. Expressed in a variety of tissues, ARFRP1 interacts with SYS1 and is thought to be involved in plasma membrane-related signaling events. ARFRP1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to a gene cluster on chromosome 20 that is commonly overexpressed in tumors, suggesting a role for ARFRP1 in carcinogenesis.

ADP ribosylation factor related protein 1; ARF related protein 1; ARF related protein; ARL 18; ARL18; ARP 1; ARP; ARP1; Helicase like protein NHL; MGC6837; SCG10 like protein; ARFRP_HUMAN.

10139

Cytoplasm

Human

1-100/201

ARFRP1

RBITC

KLH conjugated synthetic peptide derived from human ARFRP1

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

570nm/595nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

10139

Mouse, Rat, Dog, Sheep, Pig, Horse