ASGR2 Antilichaam - N-terminalgebied: HRP (ARP33820 P050-HRP)

Asialoglycoprotein receptor 2

HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2

433

P07307

NP_001172

Human, Rat, Pig, Yeast

The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR2

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

HDAC3; UBC; CDK6; CDK4; COPS5; TADA3; CDKN2A

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Human: 100%; Pig: 77%; Rat: 79%; Yeast: 77%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

35kDa

Yik, J.H., et al., (2002) J. Biol. Chem. 277 (43), 40844-40852

Wet Ice

311

ASGR2

ASGR2

Rabbit

Asialoglycoprotein receptor 2

NM_001181

LVVICVTGSQSEGHRGAQLQAELRSLKEAFSNFSSSTLTEVQAISTHGGS