ATP6V0A1 Antilichaam - N-terminalgebied: FITC (ARP46581_P050-FITC)

ATPase, H+ transporting, lysosomal V0 subunit a1

A1, Stv1, VPP1, Vph1, ATP6N1, ATP6N1A

535

Q93050

NP_005168

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V0A1

ATP6V0A1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. ATP6V0A1 is one of three A subunit proteins and it is associated with clathrin-coated vesicles. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. The occurrence of splice variants encoding different protein products has been reported, but the full-length natures of these transcripts have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

SEH1L; ZNF267; SNX4; UBC; CLIC1; MARCKSL1; MRPL44; SLC30A5; MRPL50; PTRH2; ATP6V1D; MRPL46; SCFD1; VAMP2; SRSF3; RPS18; RPS15; SLC25A3; PA2G4; NONO; ATP6V1E1; ATP6V1B1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

96kDa

Antonacopoulou, A.G., Anticancer Res. 28 (2B), 1221-1227 (2008)

Wet Ice

831

ATP6V0A1

ATP6V0A1

Rabbit

V-type proton ATPase 116 kDa subunit a isoform 1

NM_005177

RDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPE

A isoform 1