Benzylmethylether

Benzylmethyl ether is a derivative of HY-B0892 (Benzyl alcohol). Benzylmethyl ether is an aromatic alcohol, a colorless liquid with a mild aromatic odor. Benzylmethyl ether is an inhibitor of P450 enzyme. Benzylmethyl ether mediated Toll-Like Receptor 4 to reduce the inflammatory response of liver injury in mice[1][2][3].

538-86-3

12352005

H226

Cytochrome P450; Drug Derivative; Toll-like Receptor (TLR)

Immunology/Inflammation; Metabolic Enzyme/Protease; Others

Metabolism-sugar/lipid metabolism

Others

98.70

COCC1=CC=CC=C1

C8H10O

122.16

H226

[2]Du K, et al. Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses. Food Chem Toxicol. 2015 Dec;86:253-61.|[3]Cai C, et al. Benzyl alcohol attenuates acetaminophen-induced acute liver injury in a Toll-like receptor-4-dependent pattern in mice. Hepatology. 2014 Sep;60 (3) :990-1002.|[1]Friedlander G, et al. Benzyl alcohol increases membrane fluidity and modulates cyclic AMP synthesis in intact renal epithelial cells. Biochim Biophys Acta. 1987 Oct 2;903 (2) :341-8.

Room Temperature

Store at room temperature 3 years

http://file.medchemexpress.com/batch_PDF/HY-W012837/

Natural Products

No Development Reported

TLR4