CARS Antilichaam - C-terminal regio : HRP (ARP40295 P050-HRP)

Cysteinyl-tRNA synthetase

CARS, MDBH, CYSRS, MCDDBH, MGC:11246

833

NP_001014438

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human CARS

CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

UBC; DNM1L; CAND1; LUC7L2; THUMPD3; JMJD6; XPO7; FAF1; SEC23A; SEC24D; HIRIP3; HIST1H4A; TTC1; TROVE2; SHMT1; PPM1G; PPAT; PAWR; KARS; IDE; HSPA4; GFPT1; GART; GARS; APEH; APP; SUMO2; PACSIN1; PACSIN3; PACSIN2; PSTPIP1; EEF1G

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 79%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 85%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

81kDa

Kimura, K., (2006) Genome Res. 16 (1), 55-65

Wet Ice

738

CARS

CARS

Rabbit

NM_001014438

KRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHD