CBFA2T3 Antilichaam - N-terminalgebied: HRP (ARP33993 P050-HRP)

Core-binding factor, runt domain, alpha subunit 2; translocated to, 3

ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3

863

O75082

NP_787127

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the N terminal region of human CBFA2T3

The t (16;21) (q24; q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.

Zbtb38; Zbtb4; ZBTB33; GMEB2; SEC24A; MATN2; ZBTB47; UBC; RUNX1; TAL1; TRIM33; SIN3B; NCOR1; HDAC3; CBFA2T3; CBFA2T2; HDAC1; PRKAR2A; RUNX1T1; LDB1; TCF3; HDAC8; HDAC6; HDAC2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

CBFA2T3 is supported by BioGPS gene expression data to be expressed in Jurkat, MCF7

0.5 mg/ml

Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 85%; Human: 100%; Mouse: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

62kDa

Powell, J.A., et al., (2002) Genomics 80 (3), 303-310

Wet Ice

567

CBFA2T3

CBFA2T3

Rabbit

Protein CBFA2T3

NM_175931

QPRSTPPSMPPPPPAASQGATRPPSFTPHTLMNGSSHSPTAINGAPCTPN