CCR8 Proteïne (N-Flag-Strep & C-His, Human)

CCR8

CC-CKR-8, CCR-8, CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, GPRCY6, TER1

N-Flag-Strep & C-His

< 1.0 EU per μg protein as determined by the LAL method.

≥ 85 % as determined by SDS-PAGE.

1. Immobilized Recombinant Human CCR8-Nanodisc Protein (Cat:11450-H91H-NA) at 5 μg/mL (100 μL/well) can bind BMS-986340-Derived Anti-Human CCR8 Monoclonal Antibody, Human IgG1, the EC50 is 2-10 ng/mL (QC tested) . 2. Immobilized Recombinant Human CCR8-Nanodisc Protein (Cat:11450-H91H-NA) at 5 μg/mL (100 μL/well) can bind S-531011-Derived Anti-Human CCR8 Monoclonal Antibody, Human IgG1, the EC50 is 3-10 ng/mL (Routinely tested) . 3. Immobilized Recombinant Human CCR8-Nanodisc Protein (Cat:11450-H91H-NA) at 5 μg/mL (100 μL/well) can bind JTX-1811-Derived Anti-Human CCR8 Monoclonal Antibody, Human IgG1, the EC50 is 3-10 ng/mL (Routinely tested) . 4.Loaded BMS-986340-Derived Anti-CCR8 Antibody, Human IgG1 on proA Biosensor, can bind Recombinant Human CCR8 Protein, Nanodisc, Flag-Strep & His tag (Cat. No. 11450-H91H-NA) with an affinity constant of 2.380 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 5.Loaded S-531011-Derived Anti-CCR8 Antibody, Human IgG1 on proA Biosensor, can bind Recombinant Human CCR8 Protein, Nanodisc, Flag-Strep & His tag (Cat. No. 11450-H91H-NA) with an affinity constant of 1.550 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 6.Loaded JTX-1811-Derived Anti-CCR8 Antibody, Human IgG1 on proA Biosensor, can bind Recombinant Human CCR8 Protein, Nanodisc, Flag-Strep & His tag (Cat. No. 11450-H91H-NA) with an affinity constant of 2.460 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Met1-Cys228 & Asn230-Ser318

The recombinant Human CCR8 protein predicts a molecular mass of 46.51 kDa. The recombinant protein migrates as an approximately 96.9 kDa (dimer) and 44 kDa protein in SDS-PAGE under reducing conditions.

Human