CD40 Ligand Proteine, Mouse, Recombinant (monomeric hFc)

>95%

CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc) is expressed in HEK293 mammalian cells with N-monomeric hFc tag. The predicted molecular weight is 75.6 kDa and the accession number is P27548.

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