CLK1 Antilichaam - N-terminalgebied: HRP (ARP52021 P050-HRP)

CDC-like kinase 1

CLK, STY, CLK/STY

1195

P49759

NP_004062

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human CLK1

This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene.

KRTAP10-7; PDE9A; PRMT5; SRPK2; SRPK1; CLK1; BAG3; PIAS4; ISG15; UBC; YWHAG; LUC7L3; PPIG; SRSF6; PRPF4; GOLM1; UBL5; SRSF1; PTPN1; MBP; BCLAF1; NCOR1; SRSF3; SAFB

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

CLK1 is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

57kDa

Wet Ice

484

CLK1

CLK1

Rabbit

Dual specificity protein kinase CLK1

NM_004071

HSSAQENKRCKYNHSKMCDSHYLESRSINEKDYHSRRYIDEYRNDYTQGC