CTBP2 Antilichaam - C-terminalgebied: HRP (ARP50670_P050-HRP)

C-terminal binding protein 2

1488

P56545

NP_073713

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human CTBP2

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely.This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.

NOL4; TGIF1; HOXB5; NOL4L; FUNDC1; FOXP2; RIMBP3; LCOR; ZNF750; DMRTB1; TSHZ3; BCAS3; BAZ2B; PLCB1; IKZF2; RAI2; ZBTB18; IKZF1; CTBP1; FLI1; SUMO2; SUMO3; SPRTN; SMAD6; UBC; SUMO1; NEDD8; TRNT1; DDX19B; SGTA; DYRK1B; NRIP1; ZNF512B; C15orf39; CTPS2; PPP1R

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

CTBP2 is strongly supported by BioGPS gene expression data to be expressed in HeLa

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

106kDa

Dammer, E.B. (2008) J. Biol. Chem. 283 (11), 6925-6934

Wet Ice

985

CTBP2

CTBP2

Rabbit

C-terminal-binding protein 2

NM_022802

TGRIPESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVA