(D-Pro7) -Angiotensine I/II (1-7)

(D-Pro7) -Angiotensin I/II (1-7) is a selective, peptide-based antagonist of Angiotensin- (1-7) . (D-Pro7) -Angiotensin I/II (1-7) potently blocks multiple biological effects of Ang- (1-7) . (D-Pro7) -Angiotensin I/II (1-7) inhibits the hypertensive response induced by microinjection of Ang- (1-7) into the rostral ventrolateral medulla (RVLM) and abolishes the endothelium-dependent vasorelaxation of mouse. (D-Pro7) -Angiotensin I/II (1-7) can be used for the study of cardiovascular diseases[1].

586962-44-9

12352100

Angiotensin Receptor

GPCR/G Protein

Cardiovascular Disease

99.86

DMSO : 10 mg/mL (ultrasonic) |H2O : 7.69 mg/mL (ultrasonic)

OC(C=C1)=CC=C1C[C@H](NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CN=CN2)C(N3[C@H](CCC3)C(O)=O)=O)=O)=O

C41H62N12O11

899.00

[1]Santos RA, et al. Characterization of a new selective antagonist for angiotensin- (1-7), D-pro7-angiotensin- (1-7) . Hypertension. 2003 Mar;41 (3 Pt 2) :737-43.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-P1656/

Reference compound1

No Development Reported