DDOST Antilichaam - N-terminal regio : HRP (ARP46585_T100-HRP)

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase

OST, WBP1, AGER1, CDG1R, GATD6, OST48, OKSWcl45

1650

Q5VWA5

NP_005207

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human DDOST

DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.

HUWE1; VAPB; UBC; FAF1; STAU1; ASB11; TRIM13; SUZ12; EED; CLN3; NXT1; SRSF11; FN1; ATF2; STT3B; MAGT1; ZMPSTE24; VDAC2; SSR4; SSR3; SLC25A3; ILF2; KRTCAP2; FBXO6; UBD; AMFR; AUP1; TMEM173; UNC93B1; MAPK6; HDAC5; AGO3; BRCC3; GSTK1; TMBIM4; PGRMC1; SAP18

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

46kDa

Shibatani, T., (2005) Biochemistry 44 (16), 5982-5992

Wet Ice

456

DDOST

DDOST

Rabbit

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

NM_005216

SPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFD