DDX28 Antilichaam - N-terminalgebied: HRP (ARP36457_P050-HRP)

DEAD (Asp-Glu-Ala-Asp) box polypeptide 28

MDDX28

55794

Q9NUL7

NP_060850

Human, Mouse, Rat, Cow, Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human DDX28

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX28 is an RNA-dependent ATPase. DDX28 is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is intronless. It encodes an RNA-dependent ATPase. The encoded protein is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus.

MRPL52; TMEM43; MRPL57; MRPL9; MRPL11; MRPL32; MRPL17; MFF; ATP6V1H; ATP6V1D; MRPL2; MRPL42; TCIRG1; RAB11B; LAMTOR3; RBMS2; PCDH7; ILF2; ICT1; ATP6V1A; CUL3; SH3KBP1; HNRNPA1; Ybx1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 79%; Human: 100%; Mouse: 83%; Pig: 85%; Rat: 83%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

59kDa

Valgardsdottir, R. (2003) J. Biol. Chem. 278 (23), 21146-21154

Wet Ice

540

DDX28

DDX28

Rabbit

Probable ATP-dependent RNA helicase DDX28

NM_018380

FSIERAQQEAPAVRKLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQS