Dehydro-abiëtisch zuur

Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice[1][2].

[1740-19-8]

12352005

H301, H400, H410

Antibiotic; Bacterial; Fungal; PPAR

Natural Products

Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

COVID-19-anti-virus

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

https://www.medchemexpress.com/dehydroabietic-acid.html

99.75

DMSO : 100 mg/mL (ultrasonic)

O=C([C@]1(C)CCC[C@]2(C)C3=C(CC[C@@]12[H])C=C(C(C)C)C=C3)O

C20H28O2

300.44

H301, H400, H410

[1]Kim E, et al. Dehydroabietic Acid Suppresses Inflammatory Response Via Suppression of Src-, Syk-, and TAK1-Mediated Pathways. Int J Mol Sci. 2019 Mar 29;20 (7) :1593. |[2]Xie Z, et al. Dehydroabietic acid alleviates high fat diet-induced insulin resistance and hepatic steatosis through dual activation of PPAR-γ and PPAR-α. Biomed Pharmacother. 2020 Jul;127:110155.

Room Temperature

4°C (Powder, protect from light)

http://file.medchemexpress.com/batch_PDF/HY-N6869/Dehydroabietic-acid-SDS-MedChemExpress.pdf

Natural Products

Phase 4