DHX16 Antilichaam - N-terminalgebied: FITC (ARP37711_P050-FITC)

DEAH (Asp-Glu-Ala-His) box polypeptide 16

DBP2, PRP8, Prp2, DDX16, NMOAS, PRPF2, PRO2014

8449

O60231

NP_003578

Human, Mouse, Rat, Cow, Goat, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human DHX16

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked.

NUDCD1; UBC; GPKOW; SF3B2; DHX38; DGCR14; CSNK2A1; XAB2; HELQ; PYROXD1; NAA40; LSM2; MIF4GD; GON4L; WDR44; EHD2; LSM5; LSM6; GCC2; TCEA2; MTR; GSPT1; GABPB1; APP; COIL; SNRNP27; SNRNP40; SIRT7; MEGF10; Bud13; TADA2A; SRRM2; SRRM1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

DHX16 is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 86%; Goat: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Pig: 85%; Rabbit: 77%; Rat: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

115kDa

Beausoleil, S.A., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135

Wet Ice

1041

DHX16

DHX16

Rabbit

Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

NM_003587

KYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPV