DHX58 Antilichaam - N-terminalgebied: FITC (ARP36500_P050-FITC)

DEXH (Asp-Glu-X-His) box polypeptide 58

LGP2, RLR-3, D11LGP2, D11lgp2e

79132

Q96C10

NP_077024

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human DHX58

DHX58 is the negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA. Bin

USP21; APP; UBD; NKRF; CDKN2AIP; AGO2; STAU2; DICER1; DHX30; XRN2; STAU1; EIF2AK2; EIF6; AP2B1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 91%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

76kDa

Komuro, A. (2006) J. Virol. 80 (24), 12332-12342

Wet Ice

678

DHX58

DHX58

Rabbit

Probable ATP-dependent RNA helicase DHX58

NM_024119

AYVAKRHLETVDGAKVVVLVNRVHLVTQHGEEFRRMLDGRWTVTTLSGDM